OpenPrescribing papers
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Data-Driven Identification of Potentially Successful Intervention Implementations Using 5 Years of Opioid Prescribing Data
By applying one of our existing analysis tools to a national dataset, we were able to rank NHS organisations by reduction in opioid prescribing rates. Highly ranked organisations are candidates for further qualitative research into intervention design and implementation.
Status: Published
Categories
- OpenPrescribing
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Educational interventions delivered to prescribing advisers to influence primary care prescribing: a very low-cost pragmatic randomised trial using routine data from OpenPrescribing.net
A low cost randomised trial of an educational intervention in CCGs to influence prescribing of low-priority items
Status: Preprint
Categories
- OpenPrescribing
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Data-Driven Identification of Unusual Prescribing Behavior: Analysis and Use of an Interactive Data Tool Using 6 Months of Primary Care Data From 6500 Practices in England
Data-driven approaches have the potential to overcome existing biases with regard to the planning and execution of audits, interventions, and policy making within NHS organizations, potentially revealing new targets for improved health care service delivery.
Status: Published
Categories
- OpenPrescribing
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Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review
A new method for prioritizing prescribing outliers for clinical review with discussion of two illustrative examples of anti-psychotics
Status: Published
Categories
- OpenPrescribing
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Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care
JMIR EHR design paper
Status: Published
Categories
- OpenPrescribing
- Policy Insights
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Suboptimal prescribing behaviour associated with clinical software design features: a retrospective cohort study in English NHS primary care
EHR design paper
Status: Published
Categories
- OpenPrescribing
- Research Integrity
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Prescription of suboptimal statin treatment regimens: a retrospective cohort study of trends and variation in English primary care
BJGP statins paper
Status: Published
Categories
- OpenPrescribing
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The NHS deserves better use of hospital medicines data
Hospitals Data BMJ Paper.
Status: Published
Categories
- OpenPrescribing
- Policy Insights
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Trends and variation in unsafe prescribing of methotrexate: a cohort study in English NHS primary care.
Describing trends and geographical variation in methotrexate prescribing that breaches national safety recommendation
Status: Published
Categories
- OpenPrescribing
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Variation in responsiveness to warranted behaviour change among NHS clinicians: novel implementation of change detection methods in longitudinal prescribing data
Determining how clinicians vary in their response to new guidance on existing or new interventions
Status: Published
Categories
- OpenPrescribing
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Impact of Chief Medical Officer activity on prescribing of antibiotics in England: an interrupted time series analysis
Determining if there was a measurable impact from the 5 year antimicrobial resistance strategy on overall antibiotic prescribing in NHS primary care in England.
Status: Published
Categories
- OpenPrescribing
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Is Use of Homeopathy Associated With Poor Prescribing in English Primary Care? A Cross-Sectional Study
Prescribing of homeopathy still occurs in a small minority of English general practices. We hypothesised that practices that prescribe any homeopathic preparations might differ in their prescribing of other drugs.
Status: Published
Categories
- OpenPrescribing
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Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data.
Comparing prescribing variation for a number of common drugs between practices which have an in-house dispensary with those that don't.
Status: Published
Categories
- OpenPrescribing
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Measuring the Impact of an Open Web-Based Prescribing Data Analysis Service on Clinical Practice: Cohort Study on NHS England Data
Measuring the impact of OpenPrescribing being viewed on subsequent prescribing.
Status: Published
Categories
- OpenPrescribing
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Why did some practices not implement new antibiotic prescribing guidelines on urinary tract infection? A cohort study and survey in NHS England primary care
Describing trends and geographical variation in prescribing of trimethoprim and nitrofurantoin to treat urinary tract infections
Status: Published
Categories
- OpenPrescribing
- Policy Insights
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Opioid prescribing trends and geographical variation in England, 1998–2018: a retrospective database study
Our findings support calls for greater action to promote best practice in chronic pain prescribing and to reduce geographical variation.
Status: Published
Categories
- OpenPrescribing
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Six months on – NHS England needs to focus on dissemination, implementation and audit of its Low-Priority Initiative
A letter to the JRSM, describing the changes in prescribing following the first six months of guidance on low-prioirty medicines from NHS England.
Status: Published
Categories
- OpenPrescribing
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Time trends and geographical variation in prescribing of antibiotics in England 1998–2017
Despite a general trend towards more optimal antibiotic prescribing, considerable geographical variation persists across England's practices and CCGs.
Status: Published
Categories
- OpenPrescribing
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Reply to Comment on 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'
Replying to comment on paper: 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'
Status: Published
Categories
- OpenPrescribing
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Detecting Change in Comparison to Peers in NHS Prescribing Data: a Novel Application of Cumulative Sum Methodology
The CUSUM method appears to effectively discriminate between random noise and sustained change in prescribing behaviour. This method aims to allow practices and CCGs to be informed of important changes quickly, with a view to improve their prescribing behaviour.
Status: Published
Categories
- OpenPrescribing
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Pregabalin: what the patent litigation means for doctors and drug companies
Explaining the arguments over the Pregabalin patent case and explore the wider implications for the NHS and drug development
Status: Published
Categories
- OpenPrescribing
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The clinician impact and financial cost to the NHS of litigation over pregabalin: a cohort study in English primary care
Describing the variation in prescribing of pregabalin as branded Lyrica, geographically and over time
Status: Published
Categories
- OpenPrescribing
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Trends and variation in prescribing of low-priority treatments identified by NHS England: a cross-sectional study and interactive data tool in English primary care
Prescribing of low-value treatments is extensive but varies widely by treatment, geographic area and individual practice. Despite a fall in prescription numbers, the overall cost of prescribing for low-value items has risen.
Status: Published
Categories
- OpenPrescribing
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Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017
Our findings strongly support the case for comparative effectiveness trials of current diabetes drugs.
Status: Published
Categories
- OpenPrescribing
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Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis
Measuring the uptake of tamoxifen, and the alternative raloxifene, in national prescribing data sets
Status: Published
Categories
- OpenPrescribing
- Policy Insights
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Trends, geographical variation and factors associated with prescribing of gluten-free foods in English primary care: a cross-sectional study
Gluten-free prescribing is in a state of flux, with substantial clinically unwarranted variation between practices and CCGs.
Status: Published
Categories
- OpenPrescribing
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OpenPrescribing: normalised data and software tool to research trends in English NHS primary care prescribing 1998–2016
Publicly available data can be made accessible through interactive online tools to help researchers and policy-makers explore time trends in prescribing.
Status: Published
Categories
- OpenPrescribing
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New mechanism to identify cost savings in English NHS prescribing: minimising 'price per unit', a cross-sectional study
We have developed a new method to identify and enable large potential cost savings within NHS community prescribing. Given the current pressures on the NHS, it is vital that these potential savings are realised.
Status: Published
Categories
- OpenPrescribing