Papers
Showing 159 published or preprint papers authored by the Bennett Institute.
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Identification of patients undergoing chronic kidney replacement therapy in primary and secondary care data
Identification of people receiving chronic kidney replacement therapy using primary and secondary care records compared with gold standard registry data.
Status: Published
Categories
- OpenSAFELY
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The impact of COVID-19 on azathioprine, leflunomide and methotrexate monitoring, and factors associated with change in monitoring rate
This study investigated whether disease-modifying anti-rheumatic drug (DMARD) safety monitoring was affected during the COVID-19 pandemic, with additional focus on effects within key health inequality groups.
Status: Published
Categories
- OpenSAFELY
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The impact of COVID-19 on medication reviews in English primary care
This study investigated whether the rate of medication reviews in primary care were affected during the COVID-19 pandemic, with breakdown by regional, clinical and demographic subgroups.
Status: Published
Categories
- OpenSAFELY
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Comparative safety and effectiveness of Pfizer BA.4-5 versus Sanofi during the spring 2023 COVID-19 booster vaccination programme in England
A comparison of the Pfizer BA.4-5 and Sanofi vaccines for protecting against Covid-19 during Spring 2023 booster programme in England
Status: Preprint
Categories
- OpenSAFELY
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Impact of vaccination on the association of COVID-19 with cardiovascular diseases
We quantified associations between COVID-19 diagnosis and cardiovascular diseases in different vaccination and variant eras using linked electronic health records for ~40% of the English population.
Status: Published
Categories
- OpenSAFELY
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During the COVID-19 pandemic 20 000 prostate cancer diagnoses were missed in England
This study investigated the effect of the COVID-19 pandemic on prostate cancer incidence, prevalence, and mortality in England. The pandemic led to 20 000 missed prostate cancer diagnoses in England alone.
Status: Published
Categories
- OpenSAFELY
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Measuring BMI in 22 million patients in England
This study describes the use of four derivations of BMI in OpenSAFELY.
Status: Published
Categories
- OpenSAFELY
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Weight trends amongst adults with diabetes or hypertension during the COVID-19 pandemic
Amongst adults living in England with T2D and/or hypertension, rapid pandemic weight gain was more common amongst females, younger adults, those living in more deprived areas, and those with mental health conditions.
Status: Published
Categories
- OpenSAFELY
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Safety of direct-acting oral anticoagulant (DOAC) prescribing
This study aimed to identify the proportion of those prescribed a DOAC with recorded: weight, estimated Glomerular Filtration Rate (eGFR), creatinine, creatinine clearance (CrCl) and atrial fibrillation (AF). In those with recorded AF and CrCl prescribed the study aimed to identify the proportion with a recommended DOAC dose.
Status: Published
Categories
- OpenSAFELY
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OpenSAFELY: a platform for analysing electronic health records designed for reproducible research
This paper describes OpenSAFELY's reproducibility-by-design approach in detail.
Status: Published
Categories
- OpenSAFELY
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Trends in inequalities in avoidable hospitalisations across the COVID-19 pandemic
We determine whether periods of disruption were associated with increased ‘avoidable’ hospital admissions and wider social inequalities in England.
Status: Published
Categories
- OpenSAFELY
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Educational interventions delivered to prescribing advisers to influence primary care prescribing: a very low-cost pragmatic randomised trial using routine data from OpenPrescribing.net
A low cost randomised trial of an educational intervention in CCGs to influence prescribing of low-priority items
Status: Preprint
Categories
- OpenPrescribing
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Ursodeoxycholic acid and severe COVID-19 outcomes in people with liver disease
Cohort study investigating whether ursodeoxycholic acid was associated with COVID-19 related hospitalisation and death in people with primary biliary cirrhosis and primary sclerosing cholangitis.
Status: Preprint
Categories
- OpenSAFELY
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Impact of COVID-19 on mental illness in vaccinated and unvaccinated people
This study examined associations of COVID-19 with subsequent mental illness in the pre-vaccination period of the pandemic and for unvaccinated and vaccinated people after vaccination became available.
Status: Preprint
Categories
- OpenSAFELY
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Implementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic
Germ Defence is an evidence-based interactive website that promotes behaviour change for infection control within households. To maximise the potential of Germ Defence to effectively reduce the spread of COVID-19, the intervention needed to be implemented at scale rapidly.
Status: Published
Categories
- OpenSAFELY
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Clinical and health inequality risk factors for non-COVID-related sepsis during the global COVID-19 pandemic
We used OpenSAFELY-TPP data to elucidate the association between non-Covid-19 related sepsis and a range of risk factors during the Covid-19 pandemic
Status: Published
Categories
- OpenSAFELY
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Interpreting pathology test result values with comparators (<, >) in Electronic Health Records research
A short data report about comparators in pathology test results
Status: Published
Categories
- OpenSAFELY
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Antibiotics for Common Infections in Primary Care Before, During and after the COVID-19 Pandemic and Extent of Risk-Based Prescribing: Need for Personalised Guidelines
We assessed the changes in risk-based prescribing behaviours of antibiotics for common infections in primary care during the Covid-19 pandemic
Status: Preprint
Categories
- OpenSAFELY