Papers
Showing 167 published or preprint papers authored by the Bennett Institute.
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Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review
A new method for prioritizing prescribing outliers for clinical review with discussion of two illustrative examples of anti-psychotics
Status: Published
Categories
- OpenPrescribing
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Comparative effectiveness of two- and three-dose schedules involving AZD1222 and BNT162b2 in people with kidney disease
We compared the risk of COVID-19 among people with moderate-severe kidney disease who received different combinations of Astrazeneca and Pfizer–BioNTech COVID-19 vaccine over the course of the pandemic
Status: Preprint
Categories
- OpenSAFELY
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Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community
Comparing the effectiveness of sotrovimab (a neutralising monoclonal antibody) with molnupiravir (an antiviral) in preventing severe outcomes of covid-19 in adult patients infected with SARS-CoV-2 in the community and at high risk of severe outcomes from covid-19.
Status: Published
Categories
- OpenSAFELY
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Incidence and management of inflammatory arthritis in England before and during the COVID-19 pandemic
We used OpenSAFELY to replicate key metrics from the National Early Inflammatory Arthritis Audit (NEIAA), and to assess the impact of COVID-19 on the delivery of care for people with autoimmune inflammatory arthritis in England.
Status: Published
Categories
- OpenSAFELY
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Recording of ‘COVID-19 vaccine declined’
A description of the patterns of usage of codes for COVID-19 vaccines being declined.
Status: Published
Categories
- OpenSAFELY
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Association between household composition and severe COVID-19 outcomes in older people by ethnicity
This paper aims to quantify the association between household composition and risk of severe COVID-19 by ethnicity for older individuals
Status: Published
Categories
- OpenSAFELY
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Waning effectiveness of BNT162b2 and ChAdOx1 covid-19 vaccines over six months since second dose
A cohort study to assess the extent of waning of effectiveness following a second dose of BNT162b2 and ChAdOx1 covid-19 vaccines
Status: Published
Categories
- OpenSAFELY
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Comparative effectiveness of ChAdOx1 versus BNT162b2 COVID-19 vaccines in Health and Social Care workers in England
A compararison of the effectiveness of the BNT162b2 mRNA (Pfizer-BioNTech) and the ChAdOx1 (Oxford-AstraZeneca) COVID-19 vaccines against infection and COVID-19 disease in health and social care workers.
Status: Published
Categories
- OpenSAFELY
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Representativeness of electronic health record platform OpenSAFELY-TPP data compared to the population of England
This paper investigates the representativeness of OpenSAFELY-TPP data by comparing it to national population estimates.
Status: Published
Categories
- OpenSAFELY
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Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England
This paper describes the characters of individuals who have experienced COVID-19 vaccine breakthrough after their second vaccination.
Status: Published
Categories
- OpenSAFELY
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Association between oral anticoagulants and COVID-19-related outcomes
This paper investigates the association between OACs and COVID-19 outcomes in those with atrial fibrillation and a CHA2DS2-VASc score of 2.
Status: Published
Categories
- OpenSAFELY
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Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records
This paper combines results from longitudinal cohort studies with electronic health data from OpenSAFELY, to describe how risk of long COVID varies amongst demographic and clinical factors.
Status: Published
Categories
- OpenSAFELY
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Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune modifying therapies
This paper aimed to assess the risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and in those on immune-modifying therapies.
Status: Published
Categories
- OpenSAFELY
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Safety of COVID-19 vaccination and acute neurological events
This paper investigates the potential association of COVID-19 vaccination with three acute neurological events: Guillain-Barré syndrome (GBS), transverse myelitis and Bell’s palsy.
Status: Published
Categories
- OpenSAFELY
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Impact of First UK COVID-19 Lockdown on Hospital Admissions
This study used OpenSAFELY (on behalf of NHS England), EAVEII (Scotland) and SAIL Databank (Wales) to investigate the weekly hospital admission rates for cancer, cardiovascular and respiratory conditions (excluding COVID-19) broken down by disease, sex, socioeconomic group and ethnicity group in a federated analysis across England, Scotland and Wales.
Status: Published
Categories
- OpenSAFELY
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Accident and emergency (AE) attendance in England following infection with SARS-CoV-2 Omicron or Delta
We estimate the risk of accident and emergency (AE) attendance following confirmation of SARS-CoV-2 infection in England, comparing infection with Omicron to Delta
Status: Preprint
Categories
- OpenSAFELY
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Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England
Patients with COVID-19 are thought to be at higher risk of cardiometabolic and pulmonary complications, but quantification of that risk is limited. Working on behalf of NHS England, this study aimed to describe the overall burden of these complications in survivors of severe COVID-19 using OpenSAFELY.
Status: Published
Categories
- OpenSAFELY
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Comparison of methods for predicting COVID-19-related death in the general population using the OpenSAFELY platform
This paper evaluate different methods for predicting COVID-19-related death using the OpenSAFELY platform
Status: Published
Categories
- OpenSAFELY