Papers
Showing 174 published or preprint papers authored by the Bennett Institute.
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Practice variation in the use of tests in UK primary care
A retrospective analysis of 16 million tests performed over 3.3 million patient years in 2015/16. We set out to identify tests ordered from UK primary care that are subject to the greatest between-practice variation in their use.
Status: Published
Categories
- OpenPathology
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Six months on – NHS England needs to focus on dissemination, implementation and audit of its Low-Priority Initiative
A letter to the JRSM, describing the changes in prescribing following the first six months of guidance on low-prioirty medicines from NHS England.
Status: Published
Categories
- OpenPrescribing
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Temporal trends in use of tests in UK primary care, 2000-15
Assessing the temporal change in test use in UK primary care and to identify tests with the greatest increase in use.
Status: Published
Categories
- OpenPathology
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Too few trials or too few reported trials?
Highlighting that there is a serious ongoing issue with the results of completed trials not being reported.
Categories
- Policy Insights
- TrialsTracker
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Time trends and geographical variation in prescribing of antibiotics in England 1998–2017
Despite a general trend towards more optimal antibiotic prescribing, considerable geographical variation persists across England's practices and CCGs.
Status: Published
Categories
- OpenPrescribing
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Compliance with requirement to report results on the EU Clinical Trials Register: cohort study and web resource.
Assessing compliance rates with the European Commission's requirement that all trials on the EU Clinical Trials Register (EUCTR) post results to the registry within 12 months of completion
Categories
- TrialsTracker
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Reply to Comment on 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'
Replying to comment on paper: 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'
Status: Published
Categories
- OpenPrescribing
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Why Cochrane should prioritise sharing data
Discussing Cochrane's practice on data sharing.
Categories
- Open Working
- Policy Insights
- Research Integrity
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Detecting Change in Comparison to Peers in NHS Prescribing Data: a Novel Application of Cumulative Sum Methodology
The CUSUM method appears to effectively discriminate between random noise and sustained change in prescribing behaviour. This method aims to allow practices and CCGs to be informed of important changes quickly, with a view to improve their prescribing behaviour.
Status: Published
Categories
- OpenPrescribing
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Pregabalin: what the patent litigation means for doctors and drug companies
Explaining the arguments over the Pregabalin patent case and explore the wider implications for the NHS and drug development
Status: Published
Categories
- OpenPrescribing
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The clinician impact and financial cost to the NHS of litigation over pregabalin: a cohort study in English primary care
Describing the variation in prescribing of pregabalin as branded Lyrica, geographically and over time
Status: Published
Categories
- OpenPrescribing
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Trends and variation in prescribing of low-priority treatments identified by NHS England: a cross-sectional study and interactive data tool in English primary care
Prescribing of low-value treatments is extensive but varies widely by treatment, geographic area and individual practice. Despite a fall in prescription numbers, the overall cost of prescribing for low-value items has risen.
Status: Published
Categories
- OpenPrescribing
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Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017
Our findings strongly support the case for comparative effectiveness trials of current diabetes drugs.
Status: Published
Categories
- OpenPrescribing
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Noncommercial Funders' Policies on Trial Registration, Access to Summary Results, and Individual Patient Data Availability.
Assessing trials transparency policies from a sample of noncommercial funders
Categories
- Policy Insights
- Research Integrity
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Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis
Measuring the uptake of tamoxifen, and the alternative raloxifene, in national prescribing data sets
Status: Published
Categories
- OpenPrescribing
- Policy Insights
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Trends, geographical variation and factors associated with prescribing of gluten-free foods in English primary care: a cross-sectional study
Gluten-free prescribing is in a state of flux, with substantial clinically unwarranted variation between practices and CCGs.
Status: Published
Categories
- OpenPrescribing
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A cross-sectional study of all clinicians' conflict of interest disclosures to NHS hospital employers in England 2015-2016.
Documenting how NHS trusts in the UK record and share disclosures of conflict of interest by their employees
Categories
- Policy Insights
- Research Integrity
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Variation in diagnostic test requests and outcomes: a preliminary metric for OpenPathology.net
We explored C-reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR) tests ordered across Oxfordshire NHS General Practices, and the proportion of tests that yielded an abnormal result, and identified practices that had a proportion of abnormal CRP and ESR results 3 standard deviations below the mean.
Status: Published
Categories
- OpenPathology